Progress

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Filed multiple patent applications
Designed several Smart mRNAs for targeting multiple cancer types
Lab tests successfully validated Smart mRNAs worked in actual cancer cells (Q1 2025)
Complete therapeutic nanoparticles for the above cancer indications (Q3 2025)
Complete animal studies to determine toxicity and efficacy of the above cancer treatments (Q1 2026)

Major Development Milestones

February 25, 2025 – Smart mRNA Works!

Smart mRNA turned ON in
cancer cells only

fluorescene-microscopy

Smart mRNA turned OFF
in healthy cell line (HEK293)

fluorescene-microscopy

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May 31, 2025 – Successfully Made Cell Targeting Nanoparticle!

lipid-nanoparticle

Independent analysis confirmed efficient and successful attachment of Marker1 onto lipid nanoparticles
Marker1 is a molecule that will seek out specific proteins on cancer cell surface and deliver our Smart mRNA payload
Next step, we will put Smart mRNAs inside the nanoparticles to make complete cancer targeting and killing nanoparticles.

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